Ethylene

Ethylene

SCHEMBL9718947

C=C.CC(C)(C)Cc1cc(C(=O)O)ccc1C(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
MYC P01106 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ACE2 Q9BYF1 3/20 0.41
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
TSHR P16473 1/20 0.40
EPHX2 P34913 3/20 0.38
NR1H4 Q96RI1 3/20 0.38
RXRB P28702 3/20 0.38
RXRA P19793 2/20 0.38
RXRG P48443 1/20 0.38
PTPN1 P18031 1/20 0.38
POLB P06746 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
CA4 P22748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618045 0.96 TDP1 (0.46) TDP1MYCKDM4EACE2TSHR
SCHEMBL4543961 0.82 KDM4E (0.44) TDP1MYCKDM4EACE2TSHR
SCHEMBL8778664 0.81 TDP1 (0.43) TDP1MYCKDM4EACE2TSHR
SCHEMBL23519696 0.79 TDP1 (0.41) TDP1MYCKDM4EACE2TSHR
SCHEMBL16576627 0.78 ACE2 (0.39) KDM4EACE2THRATHRBTSHR
SCHEMBL277909 0.77 ALDH1A1 (0.54) MYCKDM4EACE2THRBTSHR
SCHEMBL20052097 0.77 UNG (0.42) TDP1KDM4ETHRATHRBPTPN1
SCHEMBL10566065 0.76 ESR1 (0.46) TDP1MYCTSHREPHX2NR1H4
Benzoic Acid SCHEMBL11156159 0.76 TSHR (0.56) KDM4ETSHRPOLBL3MBTL1CTDSP1
SCHEMBL28384582 0.76 PARP1 (0.38) KDM4ETHRATHRBTSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490704-A2 Process for forming a polyester film TORAY INDUSTRIES, INC. (JP) 1992-06-17 EP disclosed