(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL8778747

CCCO.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 6/20 0.64
PSIP1 O75475 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
HSD11B1 P28845 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.45
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
MAOA P21397 1/20 0.43
LOX P28300 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL8778772 0.91 HTR6 (0.70) HTR6PSIP1L3MBTL1HSD11B1SMN1; SMN2
Propanol SCHEMBL28732212 0.84 TSHR (0.70) HTR6PSIP1HSD11B1SMN1; SMN2TSHR
(Phenylsulfonyl)Benzene SCHEMBL28237512 0.83 HTR6 (0.93) HTR6PSIP1L3MBTL1HSD11B1SMN1; SMN2
(Phenylsulfonyl)Benzene SCHEMBL11085424 0.81 HTR6 (0.50) HTR6PSIP1L3MBTL1HSD11B1SMN1; SMN2
(Phenylsulfonyl)Benzene SCHEMBL9642019 0.80 HTR6 (0.88) HTR6PSIP1L3MBTL1HSD11B1SMN1; SMN2
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.80 HTR6 (1.00) HTR6PSIP1SMN1; SMN2TSHRTDP1
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.80 HTR6 (1.00) HTR6PSIP1SMN1; SMN2TSHRTDP1
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.80 HTR6 (1.00) HTR6PSIP1SMN1; SMN2TSHRTDP1
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.80 HTR6 (1.00) HTR6PSIP1SMN1; SMN2TSHRTDP1
(Phenylsulfonyl)Benzene SCHEMBL30255 0.80 HTR6 (1.00) HTR6PSIP1SMN1; SMN2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602914-B1 Ink compositions for ink jet printing XEROX CORP (US) 1997-11-12 EP claimed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US claimed
EP-0602914-B1 Ink compositions for ink jet printing XEROX CORP (US) 1997-11-12 EP disclosed
EP-0602914-A1 Ink compositions for ink jet printing XEROX CORPORATION (US) 1994-06-22 EP disclosed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US disclosed