Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778931 | 1.00 | FAAH (0.36) | FAAHMAOAMAOBACHEEPHX2 | |
| SCHEMBL8778905 | 1.00 | FAAH (0.36) | FAAHMAOAMAOBACHEEPHX2 | |
| Trifluoroacetic Acid SCHEMBL8778897 | 0.93 | S1PR1 (0.35) | FAAH | |
| Trifluoroacetic Acid SCHEMBL8923136 | 0.93 | S1PR1 (0.35) | FAAH | |
| Trifluoroacetic Acid SCHEMBL8778926 | 0.93 | S1PR1 (0.35) | FAAH | |
| SCHEMBL526030 | 0.87 | HDAC3 (0.33) | — | |
| SCHEMBL8779144 | 0.87 | HDAC3 (0.33) | — | |
| SCHEMBL8778900 | 0.87 | HDAC3 (0.33) | — | |
| SCHEMBL8412008 | 0.86 | EPHX2 (0.37) | ACHEEPHX2 | |
| SCHEMBL9017329 | 0.85 | FAAH (0.37) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669316-B1 | Analogs of 15-deoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER IND & SANTE (FR) | 1997-07-30 | — | — | EP | disclosed |
| EP-0669316-A1 | Analogs of 15-déoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER INDUSTRIE ET SANTE (FR) | 1995-08-30 | — | — | EP | disclosed |