Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385625 | 1.00 | FAAH (0.37) | FAAHPAOXHDAC6CA12CA2 | |
| Trifluoroacetic Acid SCHEMBL9178496 | 0.92 | HDAC6 (0.40) | FAAHPAOXHDAC6CA12CA2 | |
| Trifluoroacetic Acid SCHEMBL9173999 | 0.92 | HDAC6 (0.40) | FAAHPAOXHDAC6CA12CA2 | |
| SCHEMBL525138 | 0.85 | PAOX (0.42) | PAOXHDAC6CA12CA2CA4 | |
| SCHEMBL524787 | 0.85 | PAOX (0.42) | PAOXHDAC6CA12CA2CA4 | |
| SCHEMBL8778905 | 0.85 | FAAH (0.36) | FAAH | |
| SCHEMBL8778919 | 0.85 | FAAH (0.36) | FAAH | |
| SCHEMBL8778931 | 0.85 | FAAH (0.36) | FAAH | |
| SCHEMBL8412139 | 0.84 | EPHX2 (0.38) | PAOXSLC6A5 | |
| Hydrochloric Acid SCHEMBL9173284 | 0.84 | PAOX (0.41) | PAOXHDAC6CA12CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600762-B1 | Analogues of the 15-deoxyspergualine, process for their preparation and their use as immunosuppresants | FOURNIER IND & SANTE (FR) | 1996-07-10 | — | — | EP | disclosed |
| EP-0600762-A1 | Analogues of the 15-deoxyspergualine, process for their preparation and their use as immunosuppresants | FOURNIER INDUSTRIE ET SANTE (FR) | 1994-06-08 | — | — | EP | disclosed |