Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607686 | 0.92 | POLB (0.43) | POLBMEN1KMT2AABCG2NR1I3 | |
| SCHEMBL13063429 | 0.81 | NR1I3 (0.40) | POLBMEN1KMT2ANR1I3CYP1A2 | |
| SCHEMBL8779280 | 0.72 | PDE10A (0.42) | POLBMEN1KMT2ANR1I3MAPT | |
| SCHEMBL26616705 | 0.71 | PIN1 (0.47) | POLBALDH1A1TDP1 | |
| SCHEMBL8779590 | 0.68 | MAPT (0.51) | POLBMEN1KMT2AABCG2NR1I3 | |
| SCHEMBL3787452 | 0.68 | PDE10A (0.54) | POLBMEN1KMT2AABCG2CYP1A2 | |
| SCHEMBL8777275 | 0.67 | CYP1A2 (0.48) | POLBMEN1KMT2ACYP1A2MAPT | |
| SCHEMBL8778958 | 0.67 | CYP1A2 (0.51) | POLBMEN1KMT2AABCG2CYP1A2 | |
| SCHEMBL8777283 | 0.66 | CYP1A2 (0.53) | POLBMEN1KMT2AABCG2CYP1A2 | |
| SCHEMBL9607591 | 0.66 | CYP1A2 (0.44) | MEN1KMT2AABCG2CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | POLB 4191/4885MEN1 571/4885KMT2A 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.