Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL8779368 | 0.88 | SMN1; SMN2 (0.50) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL11051554 | 0.80 | CA1 (0.65) | CSNK2A2CSNK2BCSNK2A1MAPTMEN1 | |
| SCHEMBL8779377 | 0.79 | ALDH1A1 (0.57) | MAPTMEN1KMT2ARAB9ADYRK1A | |
| SCHEMBL8246439 | 0.78 | SMN1; SMN2 (0.53) | CSNK2A2CSNK2BCSNK2A1MAPTMEN1 | |
| 4-Nitrotoluene SCHEMBL8779412 | 0.75 | GAA (0.55) | MAPTRAB9ANPC1ACHEHSD17B10 | |
| SCHEMBL5173078 | 0.74 | MEN1 (0.70) | CSNK2A2CSNK2BCSNK2A1MAPTMEN1 | |
| SCHEMBL28799002 | 0.74 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13401663 | 0.74 | ALDH1A1 (0.52) | CSNK2A2CSNK2BCSNK2A1MAPTMEN1 | |
| SCHEMBL11337854 | 0.73 | KDM4E (0.66) | CSNK2A2CSNK2BCSNK2A1MAPTMEN1 | |
| SCHEMBL11337858 | 0.73 | KDM4E (0.66) | CSNK2A2CSNK2BCSNK2A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |