Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779472 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL8779442 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL10412216 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL8427107 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL13446628 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL26639631 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL3464668 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL7711901 | 0.94 | PSMD10 (0.43) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL31615042 | 0.92 | EPHX2 (0.42) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL5556510 | 0.92 | ALDH1A1 (0.43) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208451-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. | 2021-12-28 | — | — | US | disclosed |
| US-10472404-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. (CN) | 2019-11-12 | — | — | US | disclosed |
| EP-2851429-B1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC (CN) | 2019-07-24 | — | — | EP | disclosed |
| US-9745359-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | ADDA BIOTECH INC. (CN) | 2017-08-29 | — | — | US | disclosed |
| US-20170233447-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC. (CN) | 2017-08-17 | — | — | US | disclosed |
| US-20150183847-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC. (CN) | 2015-07-02 | — | — | US | disclosed |
| EP-2851429-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | Adda Biotech Inc. (CN) | 2015-03-25 | — | — | EP | disclosed |
| EP-0507348-B1 | Superoxide dismutase derivatives | KURARAY CO (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5360914-A | Intermediates for superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5238837-A | Antiinflammatory agents, antiulcer agents | KURARAY CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0507348-A2 | Superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208451-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | GLP1R, GIPR, IAPP | PSMD10 2801/4885ALDH1A1 3111/4885KMT2A 3645/4885 |
| US-10472404-B2 | Protein and protein conjugate for diabetes treatment, and applications thereof | GLP1R, GIPR, IAPP | PSMD10 2801/4885ALDH1A1 3111/4885KMT2A 3645/4885 |
| US-20150183847-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | GLP1R, GIPR, IAPP | PSMD10 2771/4885ALDH1A1 3100/4885KMT2A 3698/4885 |
| US-20170233447-A1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | GLP1R, GIPR, IAPP | PSMD10 2801/4885ALDH1A1 3111/4885KMT2A 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.