Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779472 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL8779386 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL10412216 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL8427107 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL13446628 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL26639631 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL3464668 | 1.00 | PSMD10 (0.47) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL7711901 | 0.94 | PSMD10 (0.43) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL31615042 | 0.92 | EPHX2 (0.42) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL5556510 | 0.92 | ALDH1A1 (0.43) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507348-B1 | Superoxide dismutase derivatives | KURARAY CO (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5360914-A | Intermediates for superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5238837-A | Antiinflammatory agents, antiulcer agents | KURARAY CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0507348-A2 | Superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |