SCHEMBL8779503

SCHEMBL8779503

COc1ccc(S(=O)(=O)NCCCCc2ccccc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.82
POLB P06746 2/20 0.82
PKM P14618 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.69
TP53 P04637 1/20 0.62
GAA P10253 1/20 0.62
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
SGMS1 Q86VZ5 1/20 0.58
CYP19A1 P11511 1/20 0.58
USP2 O75604 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7109149 0.90 ALDH1A1 (1.00) ALDH1A1POLBPKMSMN1; SMN2SGMS1
SCHEMBL9278806 0.85 ALDH1A1 (0.90) ALDH1A1POLBPKMSMN1; SMN2TP53
SCHEMBL29100457 0.84 ALDH1A1 (0.71) ALDH1A1PKMSMN1; SMN2TP53GAA
SCHEMBL4521900 0.83 ALDH1A1 (0.74) ALDH1A1POLBPKMSMN1; SMN2TP53
SCHEMBL25138688 0.83 ALDH1A1 (0.85) ALDH1A1POLBPKMSMN1; SMN2GAA
SCHEMBL1287477 0.82 ALDH1A1 (0.68) ALDH1A1POLBTP53GAAMEN1
SCHEMBL31014176 0.82 MEN1 (0.76) ALDH1A1POLBPKMSMN1; SMN2MEN1
SCHEMBL7113122 0.82 ALDH1A1 (1.00) ALDH1A1POLBPKMSMN1; SMN2TP53
SCHEMBL1465523 0.81 ALDH1A1 (0.87) ALDH1A1POLBPKMSMN1; SMN2MEN1
SCHEMBL120702 0.81 ALDH1A1 (1.00) ALDH1A1POLBPKMSMN1; SMN2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439980-B Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2025-04-08 CN disclosed
CN-118439980-A Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2024-08-06 CN disclosed
CN-116375611-A Method for synthesizing difluoroalkyl compound from fatty amine 浙江工业大学 2023-07-04 CN disclosed
EP-0813519-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-12-29 EP disclosed