Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12676129 | 0.86 | TBXA2R (0.71) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL4521900 | 0.85 | ALDH1A1 (0.74) | ALDH1A1TP53GAAPOLBCA12 | |
| SCHEMBL23649334 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TP53GAAPOLBMEN1 | |
| SCHEMBL23648903 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TP53GAAPOLBMEN1 | |
| SCHEMBL4520992 | 0.83 | ALDH1A1 (0.77) | ALDH1A1TP53GAAPOLBMEN1 | |
| SCHEMBL28109013 | 0.83 | ALDH1A1 (0.61) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL407477 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TP53GAAPOLBCA1 | |
| SCHEMBL8779503 | 0.82 | ALDH1A1 (0.82) | ALDH1A1TP53GAAPOLBMEN1 | |
| SCHEMBL28808214 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TP53GAAPOLBMEN1 | |
| SCHEMBL4517737 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TP53GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |