Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876394 | 0.89 | GAA (0.43) | GAAMAPK1KMT2AALDH1A1MEN1 | |
| SCHEMBL877612 | 0.87 | GAA (0.43) | GAAMAPK1KMT2AALDH1A1MEN1 | |
| SCHEMBL877810 | 0.83 | GPR139 (0.50) | KMT2AALDH1A1MEN1TP53MMP1 | |
| SCHEMBL877171 | 0.76 | KMT2A (0.54) | GAAMAPK1KMT2AALDH1A1MEN1 | |
| SCHEMBL876636 | 0.76 | KMT2A (0.52) | KMT2AALDH1A1MEN1TP53MMP1 | |
| SCHEMBL877140 | 0.75 | MMP2 (0.51) | KMT2AALDH1A1MEN1TP53MMP1 | |
| SCHEMBL877531 | 0.75 | MMP2 (0.51) | KMT2AALDH1A1MEN1TP53MMP1 | |
| SCHEMBL878345 | 0.74 | GPR139 (0.52) | KMT2AALDH1A1MEN1TP53MMP1 | |
| SCHEMBL876684 | 0.74 | GPR139 (0.52) | KMT2AALDH1A1MEN1TP53MMP1 | |
| SCHEMBL877478 | 0.74 | GPR139 (0.50) | KMT2AALDH1A1MEN1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |