Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964256 | 0.78 | TP53 (0.40) | TSHRALDH1A1POLBMAPTLMNA | |
| SCHEMBL3658980 | 0.77 | BUB1 (0.38) | KMT2AMEN1ELANE | |
| SCHEMBL28395888 | 0.76 | NPSR1 (0.33) | ALOX15ALDH1A1 | |
| SCHEMBL28395886 | 0.76 | NPSR1 (0.36) | ALOX15MAPK1 | |
| SCHEMBL926627 | 0.75 | ALDH1A1 (0.34) | KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL11555149 | 0.75 | ELANE (0.45) | L3MBTL1KMT2AALOX15TSHRMEN1 | |
| SCHEMBL28389386 | 0.70 | HCAR2 (0.33) | LMNA | |
| SCHEMBL23878341 | 0.69 | SMN1; SMN2 (0.38) | L3MBTL1KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL23878340 | 0.69 | SMN1; SMN2 (0.38) | L3MBTL1KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL5573133 | 0.69 | ALDH1A1 (0.44) | KMT2AALOX15TSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525197-B1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOGS | SHIONOGI & CO (JP) | 1997-08-27 | — | — | EP | disclosed |
| US-5319100-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5319099-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0525197-A1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOG | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |