Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966024 | 0.79 | POLB (0.33) | TP53MAPTALDH1A1POLBLMNA | |
| SCHEMBL8779653 | 0.78 | L3MBTL1 (0.38) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL926627 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL6955467 | 0.77 | NAAA (0.37) | TP53MAPTALDH1A1LMNA | |
| SCHEMBL6959688 | 0.77 | POLB (0.31) | ALDH1A1POLBLMNA | |
| SCHEMBL28442963 | 0.76 | LMNA (0.30) | ALDH1A1LMNA | |
| SCHEMBL6958441 | 0.72 | TP53 (0.36) | TP53MAPTALDH1A1LMNA | |
| SCHEMBL9301605 | 0.70 | — | — | |
| SCHEMBL3658980 | 0.69 | BUB1 (0.38) | — | |
| SCHEMBL8779626 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |