Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146364 | 1.00 | TSHR (0.50) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL8779745 | 1.00 | TSHR (0.50) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL8508929 | 0.86 | PGK1 (0.36) | TSHRTRPA1LMNAL3MBTL1 | |
| Sulfamate SCHEMBL9451490 | 0.85 | SRC (0.46) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL11043163 | 0.85 | SRC (0.46) | TSHRTRPA1LMNAKDM4ECYP2D6 | |
| SCHEMBL6827761 | 0.80 | TRPA1 (0.48) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL7982428 | 0.80 | TRPA1 (0.48) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL26128508 | 0.80 | TRPA1 (0.48) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL9425022 | 0.78 | TSHR (0.55) | TSHRTRPA1LMNAHTR2ATAAR1 | |
| SCHEMBL22042229 | 0.78 | TSHR (0.55) | TSHRHTR2ATAAR1DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763005-A4 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0763005-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032937-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1995-12-07 | — | — | WO | disclosed |