Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634 | 0.92 | EPHX2 (0.70) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Benzene SCHEMBL28162617 | 0.92 | EPHX2 (0.70) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Acetic Acid SCHEMBL6421164 | 0.90 | NAPRT (0.70) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Hydrochloric Acid SCHEMBL9156069 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Bromide SCHEMBL5706299 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Water SCHEMBL9215020 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Fluoride SCHEMBL10885265 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| SCHEMBL11353365 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Iodide SCHEMBL5706290 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 | |
| Water SCHEMBL9215017 | 0.90 | EPHX2 (0.67) | NAPRTHSD17B10SMN1; SMN2EPHX1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525197-B1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOGS | SHIONOGI & CO (JP) | 1997-08-27 | — | — | EP | disclosed |
| US-5319100-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5319099-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0525197-A1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOG | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |