Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142693 | 0.75 | — | — | |
| SCHEMBL17758585 | 0.75 | ALDH1A1 (0.32) | LMNAALDH1A1KDM4E | |
| SCHEMBL12727665 | 0.69 | GAA (0.52) | GAALMNATAAR1KMT2AALDH1A1 | |
| SCHEMBL6681807 | 0.69 | — | — | |
| SCHEMBL10113928 | 0.69 | GAA (0.47) | GAALMNATAAR1KMT2AALDH1A1 | |
| SCHEMBL17758584 | 0.68 | MEN1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL23328424 | 0.67 | KMT2A (0.46) | GAALMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL11502752 | 0.67 | — | — | |
| SCHEMBL11502753 | 0.67 | IDO1 (0.38) | KMT2ACYP2C19BLMKDM4E | |
| Sulfuric Acid SCHEMBL28899531 | 0.67 | TDP1 (0.36) | LMNAALDH1A1SLC6A6CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635001-B1 | SUBSTITUTED THIOUREAS AS BIFUNCTIONAL CHELATORS | CYTOGEN CORP (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5585468-A | MEDICAL DIAGNOSIS; TUMOR IMAGING | CYTOGEN CORPORATION (US) | 1996-12-17 | — | — | US | disclosed |
| US-5527885-A | USEFUL FOR DELIVERING DRUGS OR RADIOISOTOPES TO TARGET ORGANS, TUMORS OR THROMBI IN VIVO | CYTOGEN CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| US-5326856-A | For radioimaging of organs or tumors | CYTOGEN CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |