SCHEMBL4142693

SCHEMBL4142693

NNCS(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779854 0.75 GAA (0.38)
SCHEMBL2689709 0.72 CA5A (0.36)
SCHEMBL8981447 0.69 PTGS1 (0.33)
SCHEMBL8742732 0.69
SCHEMBL27514099 0.67 LMNA (0.46)
SCHEMBL6681807 0.67
SCHEMBL10631931 0.67
SCHEMBL29772337 0.67
Sulfuric Acid SCHEMBL11314399 0.67
SCHEMBL15298856 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566628-A Preparation method of 2,5-dihydroxy-1,4-phenylenenaphtho bipyrimidine polymer and fiber thereof HARBIN INSTITUTE TECHNOLOGY 2016-05-11 CN disclosed
US-20090029939-A1 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. 2009-01-29 US disclosed
US-20080076738-A1 Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds GILEAD SCIENCES, INC. 2008-03-27 US disclosed
US-7253180-B2 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. (US) 2007-08-07 US disclosed
EP-1742642-A2 PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2007-01-17 EP disclosed
US-20060217410-A1 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. 2006-09-28 US disclosed
US-20060116356-A1 Phosphonate analogs of HIV integrase inhibitor compounds GILEAD SCIENCES, INC. 2006-06-01 US disclosed
WO-2005117904-A2 PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-12-15 WO disclosed
EP-1558613-A2 PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-08-03 EP disclosed
US-20040167124-A1 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. 2004-08-26 US disclosed
US-5424170-A Contrast agent KONICA CORPORATION (JP) 1995-06-13 US disclosed
EP-0650087-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1995-04-26 EP disclosed
US-5279920-A Containing a hydrazide compound KONICA CORPORATION (JP) 1994-01-18 US disclosed
US-5221593-A SILVER HALIDE PHOTOGRAPHIC MATERIALS CONTAINING NOVEL NUCLEATING AGENT KONICA CORPORATION (JP) 1993-06-22 US disclosed
EP-0539925-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1993-05-05 EP disclosed
EP-0446078-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1991-09-11 EP disclosed
US-4150993-A AMINEBORANE COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-04-24 US disclosed
US-4142030-A POLYURETHANE-SILICATE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4042536-A POLYISOCYANATE, SILICIC ACID, XEROGEL BAYER AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-3988268-A Polyurethane foam plastics which contain ionic groups BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed