Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761067 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL29361101 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1SYKPOLBLTA4H | |
| SCHEMBL1479153 | 0.76 | HPGD (0.36) | KDM4EALDH1A1POLB | |
| SCHEMBL21639011 | 0.71 | ABCB1 (0.34) | — | |
| SCHEMBL4820876 | 0.69 | GAA (0.38) | KDM4EALDH1A1CYP2C9 | |
| SCHEMBL7242976 | 0.68 | FSCN1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL30152829 | 0.68 | FSCN1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL16284728 | 0.68 | SYK (0.50) | ALDH1A1L3MBTL1SYKPOLBNPC1 | |
| SCHEMBL2325657 | 0.68 | GAA (0.36) | KDM4EALDH1A1FDFT1 | |
| SCHEMBL18256442 | 0.67 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1SYKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539057-B1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PROD (US) | 1997-07-16 | — | — | EP | disclosed |