Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242976 | 1.00 | FSCN1 (0.40) | FSCN1GAAKMT2AABL1MT-CO2 | |
| SCHEMBL27782486 | 0.84 | MGLL (0.40) | KDM4E | |
| SCHEMBL6700998 | 0.84 | HTR6 (0.36) | GAAKMT2AABL1ALDH1A1ALOX15 | |
| SCHEMBL29705150 | 0.82 | KEAP1 (0.39) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20521554 | 0.82 | KEAP1 (0.39) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL1592717 | 0.81 | ALDH1A1 (0.39) | GAAKMT2ACYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL14855345 | 0.81 | AAK1 (0.36) | GAAABL1AAK1BRD4PAX8 | |
| SCHEMBL6698787 | 0.80 | AAK1 (0.33) | GAAABL1AAK1BRD4PAX8 | |
| SCHEMBL27782494 | 0.78 | EPAS1 (0.38) | — | |
| SCHEMBL13311040 | 0.78 | PAX8 (0.41) | GAAKMT2ATSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802549-B1 | NOVEL OXOQUINOLIZINE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2023-03-01 | — | — | EP | disclosed |