Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 17/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877259 | 0.92 | EGFR (0.45) | ABCG2ABCB1ABCC1MEN1LMNA | |
| SCHEMBL5575014 | 0.91 | ABCG2 (0.44) | ABCG2ABCB1ABCC1MEN1LMNA | |
| SCHEMBL877746 | 0.91 | ABCG2 (0.48) | ABCG2ABCB1ABCC1ERBB2 | |
| SCHEMBL877263 | 0.89 | ERBB2 (0.47) | ABCG2ABCB1ABCC1MEN1LMNA | |
| SCHEMBL877747 | 0.89 | ABCG2 (0.43) | ABCG2ABCB1ABCC1MEN1LMNA | |
| SCHEMBL877745 | 0.89 | ABCG2 (0.49) | ABCG2ABCB1ABCC1ERBB2 | |
| SCHEMBL1724776 | 0.84 | ROCK2 (0.44) | ABCG2ABCB1ABCC1SYKERBB2 | |
| SCHEMBL877294 | 0.84 | ABCG2 (0.58) | ABCG2ABCB1MEN1MAPTKMT2A | |
| SCHEMBL877293 | 0.84 | ABCG2 (0.58) | ABCG2ABCB1MEN1MAPTKMT2A | |
| SCHEMBL877185 | 0.83 | EGFR (0.44) | ABCG2ABCB1ABCC1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040499-A2 | METABOLIC INHIBITORS | SURFACE LOGIX, INC. (US) | 2012-03-29 | — | — | WO | disclosed |