SCHEMBL8780328

SCHEMBL8780328

CCCN(CCC)CC(O)C(C)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
TSHR P16473 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
DRD2 P14416 1/20 0.31
NFKB1 P19838 1/20 0.31
DRD1 P21728 1/20 0.31
DRD4 P21917 1/20 0.31
DRD5 P21918 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
DRD3 P35462 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP51A1 Q16850 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3106147 0.80 ALDH1A1 (0.33) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL8780308 0.80 ALDH1A1 (0.33) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL8780307 0.79 TSHR (0.33) ALDH1A1TSHRCYP2D6
SCHEMBL1010512 0.79 TSHR (0.40) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL8780346 0.78 LMNA (0.38) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL5430728 0.76 ALDH1A1 (0.42) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL18427267 0.75 TSHR (0.36) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL19774701 0.75 TSHR (0.36) ALDH1A1RAB9ACA12CA2CA9
SCHEMBL8780318 0.75 PLA2G1B (0.39) ALDH1A1CA12CA9TSHRCYP3A4
SCHEMBL17310382 0.74 CYP1A2 (0.39) CA12CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601668-B1 Epoxy resin composition SHELL INT RESEARCH (NL) 1997-03-19 EP disclosed
EP-0601668-A2 Epoxy resin composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1994-06-15 EP disclosed