Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MGAM | O43451 | 2/20 | 0.63 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.63 |
| ▸ | SI | P14410 | 2/20 | 0.63 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780369 | 1.00 | GAA (0.63) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8780417 | 0.98 | GAA (0.61) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8780419 | 0.98 | GAA (0.61) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27508279 | 0.97 | GAA (0.60) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27515413 | 0.91 | MAPT (0.57) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27508280 | 0.90 | MAPT (0.61) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27482188 | 0.89 | MAPT (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8780426 | 0.84 | MAPT (0.59) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8780429 | 0.84 | MAPT (0.59) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL463197 | 0.82 | MAPT (0.70) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |