Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780426 | 1.00 | MAPT (0.59) | MAPTNPSR1ASAH1PLA2G4AKDM4E | |
| SCHEMBL27508279 | 0.86 | GAA (0.60) | MAPTNPSR1ASAH1PLA2G4AHPGD | |
| SCHEMBL8780417 | 0.85 | GAA (0.61) | MAPTNPSR1ASAH1PLA2G4ANPC1 | |
| SCHEMBL8780419 | 0.85 | GAA (0.61) | MAPTNPSR1ASAH1PLA2G4ANPC1 | |
| SCHEMBL8780369 | 0.84 | GAA (0.63) | MAPTNPSR1ASAH1PLA2G4ANPC1 | |
| SCHEMBL8780370 | 0.84 | GAA (0.63) | MAPTNPSR1ASAH1PLA2G4ANPC1 | |
| SCHEMBL8780473 | 0.82 | MGAM (0.65) | MAPTNPSR1ASAH1PLA2G4AKDM4E | |
| SCHEMBL7331993 | 0.79 | ALDH1A1 (0.43) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL7331999 | 0.79 | ALDH1A1 (0.43) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL7330856 | 0.78 | ALDH1A1 (0.44) | MAPTKDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |