Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GMNN | O75496 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780402 | 1.00 | TSHR (0.39) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7547693 | 0.84 | TSHR (0.40) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7547691 | 0.84 | TSHR (0.40) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7341204 | 0.82 | TSHR (0.37) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7341197 | 0.82 | TSHR (0.37) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7332125 | 0.80 | TRPA1 (0.38) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL7332122 | 0.80 | TRPA1 (0.38) | MEN1KMT2ACYP3A4SPHK2SPHK1 | |
| SCHEMBL7547708 | 0.77 | FAAH (0.46) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7547706 | 0.77 | FAAH (0.46) | TSHRMEN1KMT2ACYP3A4SPHK2 | |
| SCHEMBL7550132 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |