Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745076 | 0.85 | ESR1 (0.51) | HTR6FFAR1NQO2MTNR1AMTNR1B | |
| SCHEMBL3404726 | 0.85 | ESR1 (0.51) | HTR6FFAR1NQO2MTNR1AMTNR1B | |
| SCHEMBL3406693 | 0.85 | ESR1 (0.51) | HTR6FFAR1NQO2MTNR1AMTNR1B | |
| SCHEMBL3407321 | 0.82 | FFAR1 (0.43) | KDM4CFFAR1NQO2MTNR1AMTNR1B | |
| SCHEMBL7566057 | 0.81 | CYP11B1 (0.48) | KDM4CHTR6NQO2MTNR1AMTNR1B | |
| SCHEMBL30671703 | 0.80 | KDM4C (0.55) | KDM4CFFAR1PPARD | |
| SCHEMBL8884747 | 0.79 | MTNR1A (0.61) | NQO2MTNR1AMTNR1BPPARD | |
| SCHEMBL4077603 | 0.79 | FFAR1 (0.60) | FFAR1PPARD | |
| SCHEMBL24593623 | 0.78 | KDM4C (0.46) | KDM4CHTR6NQO2MTNR1AMTNR1B | |
| SCHEMBL15839921 | 0.78 | HTR6 (0.54) | KDM4CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759025-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995030644-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |