Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780378 | 0.87 | RARB (0.56) | MAPTSMN1; SMN2RARBALDH1A1MEN1 | |
| SCHEMBL8092224 | 0.77 | CNR2 (0.39) | SMN1; SMN2MGLLALDH1A1MEN1KMT2A | |
| SCHEMBL5327988 | 0.77 | CYP3A4 (0.44) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL2401275 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2CYP4A11CYP4F2RARB | |
| SCHEMBL20874436 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2CYP4A11CYP4F2RARB | |
| SCHEMBL4188800 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2CYP4A11CYP4F2RARB | |
| SCHEMBL4178997 | 0.76 | RARB (0.69) | MAPTSMN1; SMN2CYP4A11CYP4F2RARB | |
| Hexane SCHEMBL28004600 | 0.74 | MGLL (0.63) | MAPTSMN1; SMN2CYP4A11CYP4F2MGLL | |
| SCHEMBL19288566 | 0.74 | RARB (0.69) | MAPTSMN1; SMN2CYP4A11CYP4F2RARB | |
| SCHEMBL10986414 | 0.73 | CYP4A11 (0.73) | MAPTSMN1; SMN2CYP4A11CYP4F2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |