Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780702 | 0.96 | KDM4E (0.44) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL8780529 | 0.95 | L3MBTL1 (0.47) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL31119062 | 0.92 | KDM4E (0.47) | KDM4EATML3MBTL1CA12CA1 | |
| SCHEMBL24326559 | 0.92 | KDM4E (0.42) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL18566856 | 0.91 | L3MBTL1 (0.46) | KDM4EATML3MBTL1ALDH1A1CA12 | |
| SCHEMBL8780718 | 0.91 | L3MBTL1 (0.46) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL18406156 | 0.91 | KDM4E (0.45) | KDM4EATML3MBTL1ALDH1A1CA12 | |
| SCHEMBL430484 | 0.91 | KDM4E (0.51) | KDM4EATML3MBTL1CA12CA1 | |
| SCHEMBL880884 | 0.91 | KDM4E (0.51) | KDM4EATML3MBTL1CA12CA1 | |
| SCHEMBL29363531 | 0.91 | KDM4E (0.51) | KDM4EATML3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012212-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | KDM4E 2012/4885ATM 1965/4885L3MBTL1 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.