Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613351 | 0.90 | MAPT (0.61) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL8780569 | 0.86 | MAPT (0.70) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL8070042 | 0.85 | MAPT (0.50) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL7608437 | 0.84 | MAPT (0.67) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL8633384 | 0.83 | MAPT (0.59) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL19808829 | 0.81 | L3MBTL1 (0.54) | MAPTL3MBTL1CYP1A2P2RX3MAP4K4 | |
| SCHEMBL7615977 | 0.81 | MRGPRX4 (0.54) | MAPTL3MBTL1MRGPRX4P2RX3SMN1; SMN2 | |
| SCHEMBL7528425 | 0.80 | MAPT (1.00) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL17456362 | 0.77 | MAPT (0.59) | MAPTL3MBTL1CYP1A2GAARECQL | |
| SCHEMBL19808845 | 0.77 | L3MBTL1 (0.50) | MAPTL3MBTL1CYP1A2P2RX3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806414-A1 | Intermediates for herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-11-12 | — | — | EP | claimed |
| EP-0806414-A1 | Intermediates for herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-11-12 | — | — | EP | disclosed |