Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629482 | 0.85 | PTGER1 (0.49) | MAPTL3MBTL1GRM5P2RX3MRGPRX4 | |
| SCHEMBL8780576 | 0.83 | MAPT (0.67) | MAPTL3MBTL1GRM5CYP1A2GAA | |
| SCHEMBL7613351 | 0.81 | MAPT (0.61) | MAPTL3MBTL1GRM5ALDH1A1CYP1A2 | |
| SCHEMBL8721109 | 0.80 | F2 (0.44) | L3MBTL1GRM5CYP1A2GAARECQL | |
| SCHEMBL8780569 | 0.80 | MAPT (0.70) | MAPTL3MBTL1ALDH1A1CYP1A2GAA | |
| SCHEMBL9017227 | 0.79 | MAPT (0.52) | MAPTGRM5GAA | |
| SCHEMBL7608437 | 0.78 | MAPT (0.67) | MAPTL3MBTL1ALDH1A1CYP1A2GAA | |
| SCHEMBL192020 | 0.77 | L3MBTL1 (0.64) | L3MBTL1GRM5TP53SMN1; SMN2 | |
| SCHEMBL2663097 | 0.76 | RAF1 (0.46) | MAPTL3MBTL1GRM5ALDH1A1 | |
| SCHEMBL9017144 | 0.75 | GRM5 (0.38) | MAPTL3MBTL1GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807804-A | CONTROLLING WEEDS | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5710106-A | Substituted pyridine herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |