Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178998 | 0.85 | KCNN4 (0.43) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL31560826 | 0.83 | HDAC6 (0.43) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL405869 | 0.82 | KCNN4 (0.46) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL6400375 | 0.81 | KCNN4 (0.49) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL8591922 | 0.81 | KCNN4 (0.49) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL8636719 | 0.79 | KCNN4 (0.44) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL31612947 | 0.79 | NPSR1 (0.44) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL22407020 | 0.77 | MAPK14 (0.40) | HDAC6HDAC3HDAC1HDAC2NPC1 | |
| SCHEMBL15670481 | 0.76 | KCNN4 (0.40) | HDAC6HDAC3HDAC1HDAC2KCNN4 | |
| SCHEMBL31612949 | 0.75 | SMN1; SMN2 (0.47) | HDAC6HDAC3HDAC1HDAC2KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668859-B1 | PROCESSES FOR PREPARING 2,4-OXAZOLIDINEDIONES | DU PONT (US) | 1997-02-26 | — | — | EP | disclosed |
| US-5552554-A | Imidazole and triazole carboxylates, and processes for preparing 2,4-oxazolidinediones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0668859-A1 | PROCESSES FOR PREPARING 2,4-OXAZOLIDINEDIONES. | DU PONT (US) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011359-A1 | PROCESSES FOR PREPARING 2,4-OXAZOLIDINEDIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |