Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400375 | 0.87 | KCNN4 (0.49) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL8591922 | 0.87 | KCNN4 (0.49) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL8636719 | 0.85 | KCNN4 (0.44) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL8780648 | 0.82 | HDAC6 (0.43) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL29727285 | 0.79 | KCNN4 (0.43) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL14398864 | 0.79 | KCNN4 (0.43) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL1507033 | 0.79 | KCNN4 (0.43) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL22796312 | 0.79 | CES2 (0.42) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL8636724 | 0.79 | KCNN4 (0.41) | KCNN4CES2CES1HDAC3HDAC1 | |
| SCHEMBL8637482 | 0.79 | HDAC6 (0.40) | KCNN4CES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210032228-A1 | ELECTRO-OPTIC POLYMER | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) | 2021-02-04 | — | — | US | disclosed |
| US-20120329865-A1 | MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF | CORNING INCORPORATED | 2012-12-27 | — | — | US | disclosed |
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | GPR35, GPR65, GPR68 | KCNN4 323/4885CES2 2092/4885CES1 1181/4885 |
| US-20120329865-A1 | MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF | KCNH2, KCNJ2, KCNH3 | KCNN4 41/4885CES2 727/4885CES1 554/4885 |
| US-20210032228-A1 | ELECTRO-OPTIC POLYMER | TECR, AQP3, LAGE3 | KCNN4 111/4885CES2 4031/4885CES1 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.