SCHEMBL5860449

SCHEMBL5860449

C=CCOCCOCCOC(=O)OCCOCCOCC=C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 7/20 0.52
TP53 P04637 2/20 0.52
HIF1A Q16665 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.38
POLB P06746 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP3A4 P08684 2/20 0.35
THRB P10828 2/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
SERPINE1 P05121 1/20 0.31
CA9 Q16790 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902737 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL7265581 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL7260846 0.98 ALDH1A1 (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8780696 0.96 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9714112 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1093745 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10886350 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL50692 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10870570 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL7758024 0.91 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425840-A Electromagnetic wave modulation filter 罗伯托·皮内利 2024-01-19 CN claimed
CN-113396343-B Coated optical article PPG工业俄亥俄公司 2023-10-31 CN claimed
US-4594288-A Optical lenses having a scratch-resistant coating ESSILOR INTERNATIONAL (FR) 1986-06-10 US claimed
CN-116324591-B Ophthalmic lens with antibacterial and/or antiviral properties and method for manufacturing same 卡尔蔡司光学国际有限公司 2024-07-09 CN disclosed
CN-118185456-A Coating composition and laminate 爱天思株式会社 2024-06-14 CN disclosed
CN-118164886-A Synthesis method of peroxycarbonate 安徽长河新材料有限公司 2024-06-11 CN disclosed
CN-116589879-B Active energy ray-curable hard coating agent, hard coating layer, laminate, and substrate with inorganic oxide film 爱天思株式会社 2024-06-11 CN disclosed
CN-118165154-A Allyl diglycol carbonate sheet and efficient preparation method thereof 中国疾病预防控制中心 2024-06-11 CN disclosed
CN-118165153-A Carbon acrylic acid propylene acetic acid polymeric material for radon measurement nuclear track detection and preparation method thereof 中国疾病预防控制中心 2024-06-11 CN disclosed
CN-117940518-A Active energy ray-curable primer, undercoat layer, laminate, and metal film-coated substrate 爱天思株式会社 2024-04-26 CN disclosed
CN-117916634-A Coating liquid for forming low refractive index layer, and antireflection film 爱天思株式会社 2024-04-19 CN disclosed
US-7144529-B1 Method for molding ophthalmic lenses ESSILOR INTERNATIONAL (FR) 2006-12-05 US disclosed
EP-0787749-B1 NOVEL ALLYL ETHERS, POLYMERS AND POLYMERIC SOLID ELECTROLYTES MITSUI CHEMICALS INC (JP) 2003-04-02 EP disclosed
US-5977277-A Acrylic ester, novel allyl ether, novel allyl carbonate, acrylic ester polymer, allyl ether polymer, allyl carbonate polymer and polymeric solid electrolyte MITSUI PETROCHEMICAL INDUSTRIES, LTD (JP) 1999-11-02 US disclosed
EP-0787749-A1 NOVEL ACRYLATES, NOVEL ALLYL ETHERS, NOVEL ALLYL CARBONATES, ACRYLATE POLYMERS, ALLYL ETHER POLYMERS, ALLYL CARBONATE POLYMERS, AND SOLID POLYELECTROLYTES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5235358-A LIGHT FILTER FOR IMPROVING VISION MUTZHAS MAXIMILLIAN F (DE) 1993-08-10 US disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
US-4594288-A Optical lenses having a scratch-resistant coating ESSILOR INTERNATIONAL (FR) 1986-06-10 US disclosed