Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780546 | 0.95 | TDP1 (0.51) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL8780742 | 0.92 | ALDH1A1 (0.51) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL8780525 | 0.86 | ALDH1A1 (0.57) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28797770 | 0.86 | TDP1 (0.66) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28744945 | 0.86 | GSR (0.46) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL20227707 | 0.83 | TDP1 (0.63) | TDP1CYP1A2ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL18566830 | 0.82 | TDP1 (0.41) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL14557135 | 0.80 | ALDH1A1 (0.55) | TDP1CYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL3326446 | 0.80 | ALDH1A1 (0.40) | TDP1CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL29827886 | 0.78 | CYP1A2 (0.49) | TDP1CYP1A2ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012212-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | TDP1 2212/4885CYP1A2 820/4885ALDH1A1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.