Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23781853 | 1.00 | DNM1 (0.45) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL28134394 | 1.00 | DNM1 (0.45) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL28173042 | 0.94 | NAAA (0.49) | DNM1NAAADGKAZDHHC7NPSR1 | |
| Ammonia Solution, Strong SCHEMBL11578523 | 0.85 | DNM1 (0.44) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL5075384 | 0.80 | TLR4 (0.51) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL5076562 | 0.80 | TLR4 (0.51) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL5074137 | 0.80 | TLR4 (0.51) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL5075448 | 0.80 | TLR4 (0.51) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL28153393 | 0.79 | NAAA (0.51) | DNM1NAAADGKAZDHHC7NPSR1 | |
| SCHEMBL18995463 | 0.78 | DNM1 (0.38) | DNM1NAAADGKANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766691-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035304-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1995-12-28 | — | — | WO | disclosed |