Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780862 | 0.94 | KCNH2 (0.59) | KCNH2PKMSMN1; SMN2ALKSLC22A2 | |
| SCHEMBL8780765 | 0.93 | KCNH2 (0.55) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780851 | 0.91 | KCNH2 (0.55) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780872 | 0.87 | KCNH2 (0.63) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780762 | 0.87 | KCNH2 (0.57) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780890 | 0.87 | PKM (0.52) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780940 | 0.84 | ADORA2A (0.43) | KCNH2PKMADORA3ADORA2AADORA2B | |
| SCHEMBL8780751 | 0.84 | PKM (0.51) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780820 | 0.84 | KCNH2 (0.58) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 | |
| SCHEMBL8780927 | 0.83 | KCNH2 (0.58) | KCNH2PKMSMN1; SMN2SLC22A2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |