Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | TCF4 | P15884 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780789 | 0.93 | ADORA2A (0.41) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780815 | 0.92 | ADORA2A (0.38) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780919 | 0.90 | HRH3 (0.41) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780867 | 0.86 | KCNH2 (0.43) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780967 | 0.85 | ADORA1 (0.39) | KCNH2ADORA1MAPTKMT2ASIGMAR1 | |
| SCHEMBL8780776 | 0.85 | MAOA (0.37) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780805 | 0.84 | KCNH2 (0.65) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780777 | 0.83 | KCNH2 (0.48) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780824 | 0.83 | TDP1 (0.39) | ADORA2AKCNH2ADORA1ADORA3ADORA2B | |
| SCHEMBL8780988 | 0.82 | KCNH2 (0.41) | KCNH2ADORA1MAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |