Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780905 | 0.94 | GPR84 (0.40) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780948 | 0.92 | SLC22A2 (0.39) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780897 | 0.90 | SLC22A2 (0.46) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780788 | 0.83 | GPR84 (0.39) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780893 | 0.83 | KCNH2 (0.59) | SLC6A4KCNH2CYP1A2ALDH1A1MEN1 | |
| SCHEMBL8780826 | 0.83 | GPR84 (0.38) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780959 | 0.82 | SLC22A2 (0.40) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780869 | 0.81 | KCNH2 (0.42) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780779 | 0.81 | KCNH2 (0.51) | SLC6A4KCNH2SLC22A2ADRB1SLC47A2 | |
| SCHEMBL8780809 | 0.80 | GPR84 (0.46) | GPR84CYP1A2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |