Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780827 | 0.92 | SLC6A4 (0.44) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780959 | 0.90 | SLC22A2 (0.40) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780905 | 0.86 | GPR84 (0.40) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780770 | 0.82 | ALDH1A1 (0.36) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780897 | 0.82 | SLC22A2 (0.46) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780967 | 0.80 | ADORA1 (0.39) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780774 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2AMEN1GPR84MAPK1 | |
| SCHEMBL8780873 | 0.78 | PLA2G7 (0.37) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780988 | 0.77 | KCNH2 (0.41) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8781003 | 0.77 | KCNH2 (0.50) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |