Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.63 |
| ▸ | DRD4 | P21917 | 8/20 | 0.63 |
| ▸ | DRD3 | P35462 | 8/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23067925 | 0.85 | DRD4 (0.76) | DRD2DRD4DRD3TSHR | |
| SCHEMBL5835871 | 0.81 | HTR1B (0.64) | DRD2DRD4DRD3TSHRCYP1A2 | |
| SCHEMBL16809146 | 0.79 | HTR1B (0.66) | DRD2DRD4DRD3TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL21595945 | 0.79 | HTR1B (0.62) | DRD2DRD4DRD3TSHRCYP1A2 | |
| SCHEMBL10509067 | 0.79 | DRD2 (0.75) | DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL17308303 | 0.78 | MAPT (0.54) | DRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL6309842 | 0.78 | TDP1 (0.55) | DRD2DRD4DRD3TSHRTDP1 | |
| SCHEMBL12939855 | 0.78 | DRD4 (0.52) | DRD2DRD4DRD3HTR1BADRB2 | |
| SCHEMBL13492878 | 0.78 | DRD2 (0.52) | DRD2DRD4DRD3HTR1BADRB2 | |
| SCHEMBL2255625 | 0.77 | DRD4 (0.70) | DRD2DRD4DRD3HTR1BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |