Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.34 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780884 | 0.89 | SLC22A2 (0.32) | ALDH1A1SIGMAR1SLC22A2ADRB1SLC6A4 | |
| SCHEMBL8780750 | 0.85 | TDP1 (0.37) | ALDH1A1KCNH2RXFP1KMT2APLA2G7 | |
| SCHEMBL8781035 | 0.84 | KCNH2 (0.50) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780912 | 0.84 | SIGMAR1 (0.47) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780896 | 0.84 | KCNH2 (0.42) | ALDH1A1KCNH2RXFP1CYP3A4SMN1; SMN2 | |
| SCHEMBL8780903 | 0.82 | KCNH2 (0.38) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780752 | 0.81 | MAPT (0.45) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780889 | 0.81 | SLC22A2 (0.40) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780869 | 0.81 | KCNH2 (0.42) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780787 | 0.81 | SLC22A2 (0.39) | ALDH1A1SIGMAR1SLC22A2ADRB1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |