Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780779 | 0.86 | KCNH2 (0.51) | ALDH1A1SLC6A4KCNH2CHRM2HTR1A | |
| SCHEMBL8780869 | 0.86 | KCNH2 (0.42) | SLC6A4KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL8780893 | 0.85 | KCNH2 (0.59) | ALDH1A1SLC6A4KCNH2CHRM2HTR1A | |
| SCHEMBL8780785 | 0.83 | HRH3 (0.40) | SLC6A4KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL8780903 | 0.82 | KCNH2 (0.38) | SLC6A4KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL8780988 | 0.82 | KCNH2 (0.41) | SLC6A4KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL8781003 | 0.82 | KCNH2 (0.50) | ALDH1A1SLC6A4KCNH2CHRM2HTR1A | |
| SCHEMBL8780816 | 0.82 | KCNH2 (0.59) | PKMSLC6A4KCNH2CHRM2HTR1A | |
| SCHEMBL8780919 | 0.81 | HRH3 (0.41) | PKMKCNH2MAOB | |
| SCHEMBL8780780 | 0.80 | KCNH2 (0.42) | ALDH1A1SLC6A4KCNH2CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |