Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780929 | 0.96 | KCNH2 (0.42) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| SCHEMBL8780747 | 0.93 | KDM4E (0.42) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| SCHEMBL8780780 | 0.90 | KCNH2 (0.42) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| Fumaric Acid SCHEMBL8780803 | 0.89 | KCNH2 (0.39) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| Fumaric Acid SCHEMBL8780807 | 0.89 | KCNH2 (0.39) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| SCHEMBL8780863 | 0.89 | KCNH2 (0.41) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| SCHEMBL8780885 | 0.88 | HPGD (0.39) | KCNH2DRD3HPGDSLC6A4SLC22A2 | |
| SCHEMBL8780894 | 0.87 | KCNH2 (0.44) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| SCHEMBL8780936 | 0.86 | KCNH2 (0.54) | KCNH2CHRM2DRD3CACNA1FCACNA1D | |
| SCHEMBL8780834 | 0.85 | KMT2A (0.39) | KCNH2DRD3ALDH1A1HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |