Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780929 | 0.92 | KCNH2 (0.42) | HPGDLMNAHTTSMN1; SMN2KCNH2 | |
| SCHEMBL8780747 | 0.89 | KDM4E (0.42) | HPGDLMNAHTTSMN1; SMN2KCNH2 | |
| SCHEMBL8780864 | 0.88 | KCNH2 (0.44) | HPGDLMNAHTTSMN1; SMN2KCNH2 | |
| SCHEMBL8780759 | 0.88 | TRIM24 (0.44) | LMNABRPF1RXFP1MAPTCYP3A4 | |
| Fumaric Acid SCHEMBL8780807 | 0.85 | KCNH2 (0.39) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| Fumaric Acid SCHEMBL8780803 | 0.85 | KCNH2 (0.39) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL8780889 | 0.83 | SLC22A2 (0.40) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL8780780 | 0.81 | KCNH2 (0.42) | HPGDLMNAHTTSMN1; SMN2KCNH2 | |
| SCHEMBL8780834 | 0.81 | KMT2A (0.39) | KCNH2DRD2DRD1DRD4DRD5 | |
| SCHEMBL8780863 | 0.80 | KCNH2 (0.41) | HPGDLMNAHTTSMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |