Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780929 | 0.89 | KCNH2 (0.42) | DRD3ALDH1A1KCNH2HTR2A | |
| SCHEMBL8780747 | 0.86 | KDM4E (0.42) | DRD2DRD3HTR6ALDH1A1KCNH2 | |
| SCHEMBL8780864 | 0.85 | KCNH2 (0.44) | DRD3DRD1ALDH1A1OPRM1KCNH2 | |
| Fumaric Acid SCHEMBL8780803 | 0.83 | KCNH2 (0.39) | DRD3ALDH1A1KCNH2HTR2A | |
| Fumaric Acid SCHEMBL8780807 | 0.83 | KCNH2 (0.39) | DRD3ALDH1A1KCNH2HTR2A | |
| SCHEMBL8780974 | 0.82 | DRD2 (0.42) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8780885 | 0.81 | HPGD (0.39) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8780917 | 0.81 | NPC1 (0.49) | DRD3DRD1ALDH1A1OPRM1KCNH2 | |
| SCHEMBL8780759 | 0.79 | TRIM24 (0.44) | DRD2DRD3HTR6BRD4TP53 | |
| SCHEMBL8780780 | 0.79 | KCNH2 (0.42) | DRD3DRD1ALDH1A1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |