Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781026 | 0.85 | CYP1A2 (0.47) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL8780987 | 0.84 | CYP1A2 (0.47) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL8781013 | 0.80 | PDE4D (0.45) | SYKAURKBINCENPCYP1A2KMT2A | |
| SCHEMBL8781040 | 0.80 | SYK (0.45) | SYKAURKBINCENP | |
| SCHEMBL8781190 | 0.80 | CYP1A2 (0.44) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL7002429 | 0.78 | HTR2A (0.46) | KMT2A | |
| SCHEMBL8780866 | 0.78 | SLC2A1 (0.59) | SYKAURKBINCENPCYP1A2KMT2A | |
| SCHEMBL8781006 | 0.76 | SYK (0.47) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL8781051 | 0.75 | GPBAR1 (0.53) | CYP1A2KMT2A | |
| SCHEMBL8692330 | 0.75 | SYK (0.55) | SYKAURKBINCENPABCB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773218-A1 | N-(Piperazinylalkoxyphenyl)-N'phenylalkylurea derivatives as ACAT inhibitors for the treatment of atheroschlerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |