Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781051 | 0.86 | GPBAR1 (0.53) | SLC2A1PARP10ALDH1A1SMN1; SMN2GRIN2D | |
| SCHEMBL10636234 | 0.86 | MAPK1 (0.51) | PARP10ALDH1A1SMN1; SMN2KDM4ELPAR3 | |
| SCHEMBL8781040 | 0.82 | SYK (0.45) | SLC2A1ALDH1A1SYKAURKBINCENP | |
| SCHEMBL8781013 | 0.82 | PDE4D (0.45) | SLC2A1SMN1; SMN2CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL8781026 | 0.80 | CYP1A2 (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8780987 | 0.79 | CYP1A2 (0.47) | SLC2A1LPAR3CYP1A2TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL22159185 | 0.78 | PARP10 (0.55) | PARP10ALDH1A1SMN1; SMN2KDM4EGRIN2D | |
| SCHEMBL8780979 | 0.78 | SYK (0.54) | CYP1A2TLR8TLR7KMT2ASYK | |
| SCHEMBL28552486 | 0.77 | PARP10 (0.51) | PARP10ALDH1A1SMN1; SMN2KDM4ELPAR3 | |
| SCHEMBL9018955 | 0.77 | CYSLTR1 (0.61) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773218-A1 | N-(Piperazinylalkoxyphenyl)-N'phenylalkylurea derivatives as ACAT inhibitors for the treatment of atheroschlerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |