Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 8/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781026 | 0.99 | CYP1A2 (0.47) | CYP1A2PPARGSYKTLR8TLR7 | |
| SCHEMBL8781006 | 0.90 | SYK (0.47) | CYP1A2SYKTLR8TLR7AURKB | |
| SCHEMBL8781190 | 0.86 | CYP1A2 (0.44) | CYP1A2PPARGSYKTLR8TLR7 | |
| SCHEMBL8780979 | 0.84 | SYK (0.54) | CYP1A2SYKTLR8TLR7AURKB | |
| SCHEMBL8781114 | 0.79 | SMO (0.43) | CYP1A2SYKTLR8TLR7AURKB | |
| SCHEMBL8781013 | 0.79 | PDE4D (0.45) | CYP1A2SYKAURKBINCENPSLC2A1 | |
| SCHEMBL8781040 | 0.79 | SYK (0.45) | SYKAURKBINCENPSLC2A1 | |
| SCHEMBL8780866 | 0.79 | SLC2A1 (0.59) | CYP1A2SYKTLR8TLR7AURKB | |
| SCHEMBL462017 | 0.76 | SIGMAR1 (0.50) | PPARGSLC2A1CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL10855754 | 0.76 | SYK (0.41) | CYP1A2PPARGSYKTLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773218-A1 | N-(Piperazinylalkoxyphenyl)-N'phenylalkylurea derivatives as ACAT inhibitors for the treatment of atheroschlerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |