Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780883 | 0.81 | GPR84 (0.42) | GPR84RXFP1PLA2G7CYP1A2KMT2A | |
| SCHEMBL8780809 | 0.81 | GPR84 (0.46) | GPR84RXFP1PLA2G7CYP1A2KMT2A | |
| SCHEMBL8780970 | 0.81 | GPR84 (0.42) | GPR84RXFP1PLA2G7CYP1A2KMT2A | |
| SCHEMBL20515256 | 0.80 | RXFP1 (0.46) | RXFP1PLA2G7CYP1A2KMT2AALDH1A1 | |
| SCHEMBL8780886 | 0.77 | CYP1A2 (0.47) | GPR84RXFP1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL8780774 | 0.77 | KMT2A (0.46) | GPR84RXFP1PLA2G7CYP1A2KMT2A | |
| SCHEMBL23710639 | 0.74 | MAPK1 (0.48) | RXFP1PLA2G7CYP1A2KMT2AALDH1A1 | |
| SCHEMBL8780788 | 0.73 | GPR84 (0.39) | GPR84RXFP1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL8781046 | 0.71 | POLB (0.36) | GPR84CYP1A2ALDH1A1ADORA2BPOLB | |
| SCHEMBL8780755 | 0.71 | MAPK1 (0.47) | GPR84RXFP1CYP1A2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478401-A | Preparation process of urapidil organic base raw material | 华裕(无锡)制药有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-104262264-A | New preparation technique of urapidil hydrochloride | HEBEI YIPIN PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-102295607-A | Inverse phase transfer catalysis preparation method for urapidil | — | 2011-12-28 | — | — | CN | claimed |
| CN-117658926-A | Refining method of urapidil hydrochloride | 江苏润安制药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-116082250-A | Novel method for preparing urapidil hydrochloride | 江苏润安制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116082250-A | Novel method for preparing urapidil hydrochloride | 江苏润安制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114478401-A | Preparation process of urapidil organic base raw material | 华裕(无锡)制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478401-A | Preparation process of urapidil organic base raw material | 华裕(无锡)制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-109516960-A | A method of new prepares Urapidil | 河北品制药股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-104262264-B | A kind of preparation technology of Urapidil hydrochloride | HEBEI YIPIN PHARMACEUTICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104262264-B | A kind of preparation technology of Urapidil hydrochloride | HEBEI YIPIN PHARMACEUTICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104262264-A | New preparation technique of urapidil hydrochloride | HEBEI YIPIN PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-104262264-A | New preparation technique of urapidil hydrochloride | HEBEI YIPIN PHARMACEUTICAL CO LTD | 2015-01-07 | — | — | CN | disclosed |
| CN-102295607-B | Inverse phase transfer catalysis preparation method for urapidil | UNIV ZHENGZHOU | 2013-04-17 | — | — | CN | disclosed |
| CN-102295607-A | Inverse phase transfer catalysis preparation method for urapidil | — | 2011-12-28 | — | — | CN | disclosed |
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |