Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780886 | 0.92 | CYP1A2 (0.47) | MAPK1CYP1A2TAAR1NPSR1POLB | |
| SCHEMBL23710639 | 0.75 | MAPK1 (0.48) | MAPK1CYP1A2NPSR1POLBTSHR | |
| SCHEMBL9199477 | 0.75 | MAPK1 (0.73) | MAPK1CYP1A2TAAR1NPSR1POLB | |
| SCHEMBL8780774 | 0.74 | KMT2A (0.46) | MAPK1CYP1A2TAAR1NPSR1HSD17B10 | |
| SCHEMBL8780808 | 0.72 | TAAR1 (0.45) | MAPK1CYP1A2TAAR1RXFP1ALDH1A1 | |
| SCHEMBL8780883 | 0.71 | GPR84 (0.42) | MAPK1CYP1A2TAAR1NPSR1POLB | |
| SCHEMBL8780985 | 0.71 | GPR84 (0.42) | MAPK1CYP1A2TAAR1NPSR1POLB | |
| SCHEMBL8780970 | 0.71 | GPR84 (0.42) | MAPK1CYP1A2TAAR1NPSR1POLB | |
| SCHEMBL8780809 | 0.71 | GPR84 (0.46) | MAPK1CYP1A2NPSR1HSD17B10RXFP1 | |
| SCHEMBL20515256 | 0.70 | RXFP1 (0.46) | MAPK1CYP1A2NPSR1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |