Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 10/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877187 | 0.94 | GPR139 (0.41) | GPR139NR1H4MMP1MMP2MMP3 | |
| SCHEMBL877310 | 0.90 | MMP1 (0.44) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL874055 | 0.90 | MMP1 (0.44) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877066 | 0.90 | MMP1 (0.44) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877960 | 0.88 | GPR139 (0.42) | GPR139NR1H4MMP1MMP2MMP3 | |
| SCHEMBL876807 | 0.86 | GPR139 (0.42) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877710 | 0.86 | GPR139 (0.41) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877097 | 0.85 | EIF4EBP1 (0.39) | GPR139NR1H4MMP1MMP2MMP3 | |
| SCHEMBL876683 | 0.84 | GPR139 (0.40) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877196 | 0.83 | MMP1 (0.43) | GPR139MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |